Nucleic acid construct, viral vector, viral particle, plasmid, host cell, method of producing a viral particle and pharmaceutical composition comprising the same

The present invention belongs to the field of nucleic acid constructs, viral vectors and viral particles for use in the treatment and/or prevention of disease associated with a loss of solute carrier family 6 member 1 (SLC6A1) function such as myoclonic atonic epilepsy (MAE), MAE-like and other epilepsy indications such as Lennox-Gastaut Syndrome as well as autism spectrum disorder and schizophrenia.